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主营:神经科学领域的蛋白及抗体
℡ 4000-520-616
℡ 4000-520-616
PhosphoSolutions/Periostin Pan Antibody/1622-PERI/100 µl
产品编号:1622-PERI
市  场 价:¥4574.70
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$345.00
品      牌: PhosphoSolutions
公      司:PhosphoSolutions
公司分类:
PhosphoSolutions/Periostin Pan Antibody/1622-PERI/100 µl
商品介绍

Rabbitpolyclonalantibody

Size:
100µl
Formulation:
Affinitypurified
Specificity:
Rat,Mouse,Human,Chicken
Applications:
WB1:1,000IHC1:100
Species:
Rabbit
MolecularReference:
~93kDa
CiteThisAntibody:
PhosphoSolutionsCat#1622-PERI,RRID:AB_2492206
Antigen/Purification:ExpandCollapse

Theantigenisa peptidefromfasciclindomain1ofmouseperiostin.

Theantibodyisaffinitypurified.

BIOLOGicalSignificance:ExpandCollapse

Periostinisamatricellularprotein,i.e.anextracellularmatrixproteinthatinteractsbothwithotherECMproteinsandwithcell-surfacereceptors.Likemanyothermatricellularproteins,thefunctionofperiostinisimportantbothinembryonicdevelopmentandintheremodelingofadulttissuesinresponsetopathologicalinsults.Periostinwasoriginallyisolatedasanosteoblast-specificMarkerthatfunctionsasacelladhesionmoleculeforpreosteoblastsandisthoughttobeinvolvedinosteoblastrecruitment,attachmentandspreADIng(Kruzynska-FrejtagA.etal.,2004).Periostinhasrecentlybeenshowntopromotecollagenfibrogenesis,inhibitdifferentiationofProgenitorcellsintocardiomyocytesandtobeessentialinmaintainingthebiomechanicalpropertiesoftheadultmyocardium(Norrisetal.,2008)

Storage

LiquidinPBS.Containsnopreservative.

Forlongtermstorage–20°Cisrecommendedinundilutedaliquots.Stableat–20°Cforatleast1year.Avoidfreeze/thawcycles.

GeneralReferences

Kruzynska-FrejtagA,WangJ,RogersR,KrugE,HoffmanS,MarkwaldRR,ConwaySJ.(2004)Periostinisexpressedwithinthedevelopingteethatthesitesofepithelial-mesenchymalinteraction.DevelopDynamics,229:857-868.

NorrisRA,BorqTK,ButcherJT,BaudinoTA,BanerjeeI,MarkwaldRR(2008)Neonatalandadultcardiovascularpathophysiologicalremodelingandrepair:developmentalroleofperiostin.AnnNYAcadSci.1123:30-40.

NorrisRA,DamonB,MironovV,KasyanovV,RamamurthiA,Moreno-RodriguezR,TruskT,PottsJD,GoodwinRL,DavisJ,HoffmanS,WenX,SugiY,KernCB,MjAATvedtCH,TurnerDK,OkaT,ConwaySJ,MolkentinJD,ForgacsG,MarkwaldRR.(2007)Periostinregulatescollagenfibrillogenesisandthebiomechanicalpropertiesofconnectivetissues.JCellBiochem.101(3):695-711.

品牌介绍

PhosphoSolutions 由 Drs 于 2001 年创立。Michael D. Browning、John W. Haycock 和 Andrew J. Czernik,他们在 Paul Greengard 博士的实验室共同工作,Paul Greengard 博士因研究蛋白质磷酸化在信号转导中的作用而共同获得 2000 年诺贝尔医学奖在神经系统中。这种专业知识使我们主要关注神经科学领域中感兴趣的蛋白质。我们位于科罗拉多州奥罗拉的 Fitzsimons 生命科学园区,是一支敬业、友好、勤奋的科学家团队,致力于为您提供最优质的抗体和业内客户支持。

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