Rabbitpolyclonalantibody

Size:

100µl

Formulation:

AffinityPurifiedfromPooledSerum

Specificity:

Rat,Mouse,Human,Bovine,Chicken,Non-humanprimate,Canine

Applications:

WB1:1,000

Species:

Rabbit

GeneName:

PPP1R1B

MolecularReference:

~32kDa

CiteThisAntibody:

PhosphoSolutionsCat#p1025-137,RRID:AB_2492070

Storage

100µlin10mMHEPES(pH7.5),150mMNaCl,100µgBSApermland50%glycerol.Adequateamountofmaterialtoconduct10-miniWesternBlots.

Forlongtermstorage–20°Cisrecommended.Stableat–20°Cforatleast1year.

GeneralReferences

BibbJA,SnyderGL,NishiA,YanZ,MeijerL,FienbergAA,TsaiLH,KwonYT,GiraultJA,CzernikAJ,HuganirRL,HemmingsHC,Jr.,NairnAC,GreengardP(1999)PhosphorylationofDARPP-32bycdk5modulatesdopaminesignallinginneurons.Nature(London)402:669-671.

Fienberg,A.A.,Hiroi,N.,Mermelstein,P.G.,Song,W.,Snyder,G.L.,Nishi,A.,Cheramy,A.O’Callaghan,J.P.,Miller,D.B.,Cole,D.G.,Corbett,R.,Haile,C.N.,Cooper,D,C.,Onn,S.P.,Grace,A.A.,Ouimet,C.C.,White,F.G.,Hyman,S.E.,Surmeier,D.G.,Girault,J.,Nestler,E.J.andGreengard,P.(1998)DARPP-32:regulatoroftheefficacyofdopaminergicneurotransmission.Science281:838-842.

LindskogM,SvenningssonP,PozziL,KimY,FienbergAA,BibbJA,FredholmBB,NairnAC,GreengardP,FisoneG(2002)InvolvementofDARPP-32phosphorylationinthestimulantactionofcaffeine.Nature(London)418:774-778.

MaldveRE,ZhangTA,Ferrani-KileK,SchreiberSS,LippmannMJ,SnyderGL,FeinbergAA,LeslieSW,GonzalesRA,MorrisettRA(2002)DARPP-32andtheregulationoftheethanolsensitivityofNMDAreceptorsinthenucleusaccumbens.NatureNeurosci5:641-648.

SvenningssonP,TzavaraET,WitkinJM,FienbergAA,NomikosGG,GreengardP(2002)InvolvementofstriatalandextrastriatalDARPP-32inbiochemicalandbehavioraleffectsoffluoxetine(Prozac®).ProcNatlAcadSciUSA99:3182-3187.

PhosphoSolutions 由 Drs 于 2001 年创立。Michael D. Browning、John W. Haycock 和 Andrew J. Czernik，他们在 Paul Greengard 博士的实验室共同工作，Paul Greengard 博士因研究蛋白质磷酸化在信号转导中的作用而共同获得 2000 年诺贝尔医学奖在神经系统中。这种专业知识使我们主要关注神经科学领域中感兴趣的蛋白质。我们位于科罗拉多州奥罗拉的 Fitzsimons 生命科学园区，是一支敬业、友好、勤奋的科学家团队，致力于为您提供最优质的抗体和业内客户支持。