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主营:神经科学领域的蛋白及抗体
℡ 4000-520-616
℡ 4000-520-616
PhosphoSolutions/Actin Antibody/125-ACT/100 µl
产品编号:125-ACT
市  场 价:¥3911.70
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$295.00
品      牌: PhosphoSolutions
公      司:PhosphoSolutions
公司分类:
PhosphoSolutions/Actin Antibody/125-ACT/100 µl
商品介绍

MouseMonoclonalAntibody

Size:
100µl
Formulation:
Mouseascitesfluid
Specificity:
Xenopus,Drosophila,Zebrafish,Mostmammals,Someinvertebrates
Applications:
WB1:5,000IF1:500IHC1:500
Species:
Mouse
MolecularReference:
~42kDa
CiteThisAntibody:
PhosphoSolutionsCat#125-ACT,RRID:AB_2492035
Antigen/Purification:ExpandCollapse

Theantigenisachickengizzardactin.

Theantibodyisunpurifiedascitesfluid.

BIOLOGicalSignificance:ExpandCollapse

Actinisthemostabundantproteinfoundinvirtuallyalleukaryoticcells.Itisalsooneofthemosthighly-conservedproteins,differingbynomorethan20%inspeciesasdiverseasalgaeandhumans,makingitanexcellentchoiceforuseasaloADIngcontrol.ItisthemonomericsubunitofMICROFILaments,oneofthethreemajorcomponentsoftheCytoskeleton,andofthinfilaments,whicharepartofthecontractileapparatusinmusclecells.Thus,actinparticipatesinmanyimportantcellularfunctions,includingmusclecontraction,cellmotility,celldivisionandcytokinesis,vesicleandorganellemovement,cellsignaling,andtheestablishmentandmaintenanceofcelljunctionsandcellshape.

Storage

Liquidcontaining0.01%sodiumazide.

Forlongtermstorage–20°Cisrecommendedinundilutedaliquots.Stableat–20°Cforatleast1year. Avoidfreeze/thawcycles.

ProductSpecificReferences

Choi,Y.S.,Horning,P.,Aten,S.,Karelina,K.,Alzate-Correa,D.,Arthur,J.S.C.,Hoyt,K.R.andObrietan,K.,2017.Mitogen-andStress-ActivatedProteinKinase1RegulatesStatusEpilepticus-EvokedCellDeathintheHippocampus.ASNneuro,9(5),p.1759091417726607.PMID:28870089

Barcus,C.E.,O’Leary,K.A.,Brockman,J.L.,Rugowski,D.E.,Liu,Y.,Garcia,N.,Yu,M.,Keely,P.J.,Eliceiri,K.W.andSchuler,L.A.,2017.Elevatedcollagen-Iaugmentstumorprogressivesignals,intravasationandmetastasisofprolactin-inducedestrogenreceptoralphapositivemammarytumorcells.BreastCancerResearch,19(1),p.9.PMID:28103936

Ramena,G.,Yin,Y.,Yu,Y.,Walia,V.,&Elble,R.C.(2016).CLCA2interactorEVA1isrequiredformammaryepithelialcelldifferentiation.PloSone,11(3),e0147489.PMID:26930581

Goodfellow,M.J.,ABDulla,K.A.,&Lindquist,D.H.(2016).NeonatalethanolexposureimpairstracefearconditioningandaltersNMDAreceptorsubunitexpressioninadultmaleandfemalerats.Alcoholism:ClinicalandExperimentalResearch,40(2),309-318.PMID:26842250

Barcus,C.E.,Holt,E.C.,Keely,P.J.,Eliceiri,K.W.,&Schuler,L.A.(2015).DenseCollagen-IMatricesEnhancePro-TumOrigenicEstrogen-ProlactinCrosstalkinMCF-7andT47DBreastCancerCells.PloSone,10(1)e0116891.PMID:25607819

品牌介绍

PhosphoSolutions 由 Drs 于 2001 年创立。Michael D. Browning、John W. Haycock 和 Andrew J. Czernik,他们在 Paul Greengard 博士的实验室共同工作,Paul Greengard 博士因研究蛋白质磷酸化在信号转导中的作用而共同获得 2000 年诺贝尔医学奖在神经系统中。这种专业知识使我们主要关注神经科学领域中感兴趣的蛋白质。我们位于科罗拉多州奥罗拉的 Fitzsimons 生命科学园区,是一支敬业、友好、勤奋的科学家团队,致力于为您提供最优质的抗体和业内客户支持。

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