RabbitPolyclonalAntibody
TheantigenisasyntheticpeptidecorrespondingtoaminoacidresiduesfromtheC-terminalregionofratadenylatecyclaseIIIconjugatedtoKLH.
Theantibodyis affinitypurifiedrabbitserum.
Adenylatecyclaseistheenzymewhichproducesthe“secondmessenger”signalingmolecule,cAMPfromATP.TypeIIIadenylatecyclaseislocalizedtothemembranessurroundingneuronalcilia.Muchiscurrentlyunknownaboutthefunctionofprimaryciliainvertebrates,however,recentworkhasbeguntoexploretheirroleinneuronalsignalingandneurogenesis(FuchsandSchwark,2004;LouviandGrove2011).
100μlinPBS. Storeat–20°Cinundilutedaliquots;
Forlongtermstorage–20°Cisrecommended.Stableat–20°Cforatleast1year.Avoidfreeze/thawcycles.
FuchsJL,SchwarkHD.(2004)Neuronalprimarycilia:areview.CellBiolInt.28:111-8.
LouviAandGroveEA.(2011)CiliaintheCNS:thequietorganelleclaimscenterstage.Neuron69:1046-1060.
PhosphoSolutions 由 Drs 于 2001 年创立。Michael D. Browning、John W. Haycock 和 Andrew J. Czernik,他们在 Paul Greengard 博士的实验室共同工作,Paul Greengard 博士因研究蛋白质磷酸化在信号转导中的作用而共同获得 2000 年诺贝尔医学奖在神经系统中。这种专业知识使我们主要关注神经科学领域中感兴趣的蛋白质。我们位于科罗拉多州奥罗拉的 Fitzsimons 生命科学园区,是一支敬业、友好、勤奋的科学家团队,致力于为您提供最优质的抗体和业内客户支持。