请使用支持JavaScript的浏览器!
主营:神经科学领域的蛋白及抗体
℡ 4000-520-616
℡ 4000-520-616
PhosphoSolutions/Alpha Synuclein Antibody/107-ASYN/100 µl
产品编号:107-ASYN
市  场 价:¥4574.70
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$345.00
品      牌: PhosphoSolutions
公      司:PhosphoSolutions
公司分类:
PhosphoSolutions/Alpha Synuclein Antibody/107-ASYN/100 µl
商品介绍

Mousemonoclonalantibody

Size:
100µl
Formulation:
ProteinGpurified
Specificity:
Rat,Mouse,Human
Applications:
WB1:1,000IF1:500
Species:
Mouse
GeneName:
SNCA
MolecularReference:
~15kDa
CiteThisAntibody:
PhosphoSolutionsCat#107-ASYN,RRID:AB_2492037
Antigen/Purification:ExpandCollapse

TheantigenisafulllengthhumanalphasynucleinexpressedinE.Coli.

TheantibodyisProteinGpurified.

BIOLOGicalSignificance:ExpandCollapse

Alpha-synucleinisapresynapticneuronalproteinthatisthoughttobeinvolvedintheformationofSNAREcomplexes.Mostsignificantly,aggregatedalpha-synucleinisoneofthemajorcomponentsfoundintheLewybodiesthatoccurinParkinson’sdisease(PD)andotherneurodegenerativedisorders(Okochietal.,2000).EarlyonsetParkinson’sdiseasemaybecausedbyaduplicationortriplicationofoneofthealphasynucleingenes(ChartierHarlinMCetal.,2004andSingleton,ABetal.,2005).Alpha-synucleinisalsofoundintheLewybodiesofpatientswithdiffuseLewybodydiseaseandinclusionsinglialcellsinthebrainsofpatientswithmultiplesystematrophy(MSA)andamyotrophiclateralsclerosis(ALS).

Storage

100µlliquidcontaining10mMsodiumazide.

Forlongtermstorage–20°Cisrecommendedinundilutedaliquots.Stableat–20°Cforatleast1year.Avoidfreeze/thawcycles.

GeneralReferences

OkochiM,WalterJ,KoyamaA,NakajoS,BabaM,IwatsuboT,MeijerL,KahlePJ,HaassC(2000)ConstitutivephosphorylationoftheParkinson’sdiseaseassociatedalpha-synuclein.JBiolChemJan7;275(1):390-7.

Chartier-Harlin,MC.etal.Alpha-synucleinlocusduplicationasacauseoffamilialParkinson’sdisease.Lancet364:1167-1169(2004).

Singleton,ABetal.Alpha-synucleinlocustriplicationcausesParkinson’sdisease.Science302:841(2003).

品牌介绍

PhosphoSolutions 由 Drs 于 2001 年创立。Michael D. Browning、John W. Haycock 和 Andrew J. Czernik,他们在 Paul Greengard 博士的实验室共同工作,Paul Greengard 博士因研究蛋白质磷酸化在信号转导中的作用而共同获得 2000 年诺贝尔医学奖在神经系统中。这种专业知识使我们主要关注神经科学领域中感兴趣的蛋白质。我们位于科罗拉多州奥罗拉的 Fitzsimons 生命科学园区,是一支敬业、友好、勤奋的科学家团队,致力于为您提供最优质的抗体和业内客户支持。

自营商城图标
厂家直采
全球直采 正品优价
正品保障图标
正品保障
厂家直发 有线跟踪
解放采购图标
正规清关
CIF100%正规报关,提供发票
及时交付图标
及时交付
限时必达 不达必赔