Rabbitpolyclonalantibody

Size:

100µl

Formulation:

AffinityPurifiedfromPooledSerum

Specificity:

Mouse,Rat,Human,Zenopus

Applications:

WB1:1000

Species:

Rabbit

GeneName:

CAMK2A/B

MolecularReference:

~50kDa

CiteThisAntibody:

PhosphoSolutionsCat#p1005-286,RRID:AB_2492051

Storage

100µlin10mMHEPES(pH7.5),150mMNaCl,100µgBSApermland50%glycerol.Adequateamountofmaterialtoconduct10-miniWesternBlots.

Forlongtermstorage–20°Cisrecommended.Stableat–20°Cforatleast1year.

ProductSpecificReferences

Murakoshi,H.,Shin,M.E.,Parra-Bueno,P.,Szatmari,E.M.,Shibata,A.C.andYasuda,R.,2017.KineticsofEndogenousCaMKIIRequiredforSynapticPlasticityRevealedbyOptogeneticKinaseInhibitor.Neuron.Apr5;94(1):37-47.e5.PMID:28318784

Huang,L.,Hayes,S.andYang,G.,2016.Long-lastingbehavioraleffectsinneonatalmicewithmultipleexposuresto…-xylazineanesthesia.NeurotoxicologyandTeratology.PMID:27622724

Barcomb,K.,Buard,I.,Coultrap,S.J.,Kulbe,J.R.,O’Leary,H.,Benke,T.A.,&Bayer,K.U.(2014).AutonomousCaMKIIrequiresfurtherstimulationbyCa2+/calmodulinforenhancingsynapticstrength.TheFASEBJournal,28(8),3810-3819.PMID:24843070

Bernard,P.B.,Castano,A.M.,Bayer,K.U.,&Benke,T.A.(2014).Necessary,butnotsufficient:insightsintothemechanismsofmGluRmediatedlong-termdepressionfromaratmodelofearlylifeseizures.Neuropharmacology,84,1-12.PMID:24780380

StevenJ.Coultrap,K.UlrichBayer(2014)NitricoxideinducesCa2+-independentactivityoftheCa2+/calmodulin-dependentproteinkinaseII(CaMKII).J.BiolChem.289(28):19458-65.PMID:24855644

Magupalli,V.G.,Mochida,S.,Yan,J.,Jiang,X.,Westenbroek,R.E.,Nairn,A.C.,Scheuer,T.,&Catterall,W.A.(2013).Ca2+-independentactivationofCa2+/calmodulin-dependentproteinkinaseIIboundtotheC-terminaldomainofCaV2.1calciumchannels.JournalofBiologicalChemistry,288(7),4637-4648.PMID: 23255606

W.WadeKothmann,E.BradyTrexler,ChristopherM.Whitaker,WeiLi,StephenC.Massey,andJohnO’Brien(2012)NonsynapticNMDAReceptorsMediateActivity-DependentPlasticityofGapJunctionalCouplingintheAllAmacrineCellNetwork.J.Neurosci.32(3):6747-6759.PMID:22593045

RebekahS.Vest,HeatherO’Leary,StevenJ.Coultrap,MarkS.Kindy,andK.UlrichBayer(2010)EffectivePost-insultNeuroprotectionbyaNovelCa2+/Calmodulin-dependentProteinKinaseII(CaMKII)InhibitorJ.Biol.Chem.,285:20675–20682.PMID:20424167

StevenJ.Coultrap,IsabelleBuard,JaquelineR.Kulbe,MarkL.Dell’Acqua,andK.UlrichBayer(2010)CaMKIIAutonomyIsSubstrate-dependentandFurtherStimulatedbyCa2+/CalmodulinJ.Biol.Chem.,285:17930–17937.PMID:20353941

KurtisD.Davies,SusanM.Goebel-Goody,StevenJ.Coultrap,andMichaelD.Browning(2008)LongTermSynapticDepressionThatIsAssociatedwithGluR1DephosphorylationbutNotAmino-3-hydroxy-5-methyl-4-isoxazolepropionicAcid(AMPA)ReceptorInternalizationJ.Biol.Chem.,283:33138–33146.PMID:18819923

XiuSun,MichaelMilovanovic,YunZhao,andMarinaE.Wolf(2008)AcuteandChronicDopamineReceptorStimulationModulatesAMPAReceptorTraffickinginNucleusAccumbensNeuronsCoculturedwithPrefrontalCortexNeurons.J.Neurosci.,28:4216–4230.PMID:18417701

MatthewTownsend,TapanMehta,andDennisJ.Selkoe(2007)SolubleA-betaInhibitsSpecificSignalTransductionCascadesCommontotheInsulinReceptorPathway.J.Biol.Chem.,282:33305–33312.PMID:17855343

RebekahS.Vest,KurtisD.Davies,HeatherO’Leary,J.DavidPort,andK.UlrichBayer(2007)DualMechanismofaNaturalCaMKIIInhibitor.Mol.Biol.Cell,18:5024–5033.PMID:17942605

PhosphoSolutions 由 Drs 于 2001 年创立。Michael D. Browning、John W. Haycock 和 Andrew J. Czernik，他们在 Paul Greengard 博士的实验室共同工作，Paul Greengard 博士因研究蛋白质磷酸化在信号转导中的作用而共同获得 2000 年诺贝尔医学奖在神经系统中。这种专业知识使我们主要关注神经科学领域中感兴趣的蛋白质。我们位于科罗拉多州奥罗拉的 Fitzsimons 生命科学园区，是一支敬业、友好、勤奋的科学家团队，致力于为您提供最优质的抗体和业内客户支持。