Rabbitpolyclonalantibody

Size:

150µl

Formulation:

AffinityPurifiedfromPooledSerum

Specificity:

Rat,Mouse,Human,Chicken,Canine

Applications:

WB1:1,000

Species:

Rabbit

GeneName:

GRIA1

MolecularReference:

~100kDa

CiteThisAntibody:

PhosphoSolutionsCat#p1160-831,RRID:AB_2492127

Storage

100µlin10mMHEPES(pH7.5),150mMNaCl,100µgBSApermland50%glycerol.Adequateamountofmaterialtoconduct10-miniWesternBlots.

Forlongtermstorage–20°Cisrecommended.Stableat–20°Cforatleast1year.

ProductSpecificReferences

Lameth,J.,Gervais,A.,Colin,C.,Lévêque,P.,Jay,T.M.,Edeline,J.M.andMallat,M.,2017.AcuteNeuroinflammationPromotesCellResponsesto1800MHzGSMElectromagneticFieldsintheRatCerebralCortex.NeurotoxicityResearch,pp.1-16.PMID:28578480

O’Leary,H.,Bernard,P.B.,Castano,A.M.,&Benke,T.A.(2016).EnhancedlongtermpotentiationanddecreasedAMPAreceptordesensitizationintheacuteperiodfollowingasinglekainateinducedearlylifeseizure.Neurobiologyofdisease,87,134-144.PMID:26706598

Xue,B.,Chen,E.C.,He,N.,Jin,D.Z.,Mao,L.M.,&Wang,J.Q.(2016).IntegratedregulationofAMPAglutamatereceptorphosphorylationinthestriatumbydopamineandacetylcholine.Neuropharmacology.PMID:27060412

Mao,L.M.,Xue,B.,Jin,D.Z.,&Wang,J.Q.(2015).DynamicincreasesinAMPAreceptorphosphorylationintherathippocampusinresponsetoamphetamine.Journalofneurochemistry.Jun;133(6):795-805.PMID:25689263

Pasek,J.G.,Wang,X.,&Colbran,R.J.(2015).DifferentialCaMKIIregulationbyvoltage-gatedcalciumchannelsinthestriatum.MolecularandCellularNeuroscience,68,234-243. PMID:26255006

Mao,L.M.,Hastings,J.M.,Fibuch,E.E.,&Wang,J.Q.(2014).PropofolselectivelyaltersGluA1AMPAreceptorphosphorylationinthehippocampusbutnotprefrontalcortexinyoungandagedmice.Europeanjournalofpharmacology,738,237-244. PMID:24907515

Xue,B.,Edwards,M.C.,Mao,L.M.,Guo,M.L.,Jin,D.Z.,Fibuch,E.E.,&Wang,J.Q.(2014).RapidandsustainedGluA1S845phosphorylationinsynapticandextrasynapticlocationsintheratforebrainfollowingamphetamineadmiNISTration.Neurochemistryinternational,64,48-54. PMID:24231469

Barcomb,K.,Coultrap,S.J.,&Bayer,K.U.(2013).EnzymaticactivityofCaMKIIisnotrequiredforitsinteractionwiththeglutamatereceptorsubunitGluN2B.Molecularpharmacology,84(6),834-843.PMID:24056996

YuxiaJiao,NidhiJalan-Sakrikar,A.J.Robison,AnthonyJ.Baucum,II,MarthaA.Bass,andRogerJ.Colbran(2011)CharacterizationofaCentralCa²⁺/Calmodulin-dependentProteinKinaseIIα/βBindingDomaininDensinThatSelectivelyModulatesGlutamateReceptorSubunitPhosphorylation.J.Biol.Chem.286:24806–24818. PMID:21610080

StevenJ.Coultrap,IsabelleBuard,JaquelineR.Kulbe,MarkL.Dell’Acqua,andK.UlrichBayer(2010)CaMKIIAutonomyIsSubstrate-dependentandFurtherStimulatedbyCa²⁺/Calmodulin.J.Biol.Chem.,285:17930–1793. PMID:20353941

RobertM.Sears,Rong-JianLiu,NandakumarS.Narayanan,RuthSharf,MarkF.Yeckel,MarkLaubach,GeorgeK.Aghajanian,andRalphJ.DiLeone(2010)RegulationofNucleusAccumbensActivitybytheHypothalamicNeuropeptideMelanin-ConcentratingHormoneJ.Neurosci.,30:8263–8273.PMID:20554878

KurtisD.Davies,SusanM.Goebel-Goody,StevenJ.Coultrap,andMichaelD.Browning(2008)LongTermSynapticDepressionThatIsAssociatedwithGluR1DephosphorylationbutNotα-Amino-3-hydroxy-5-methyl-4-isoxazolepropionicAcid(AMPA)ReceptorInternalizationJ.Biol.Chem.,283:33138–33146.PMID:18819923

SergioLeal-Ortiz,ClarissaL.Waites,RyanTerry-Lorenzo,PedroZamorano,EckartD.Gundelfinger,andCraigC.Garner(2008)PiccolomodulationofSynapsin1adynamicsregulatessynapticvesicleexocytosis.J.CellBiol.,181:831–846.PMID:18519737

PhosphoSolutions 由 Drs 于 2001 年创立。Michael D. Browning、John W. Haycock 和 Andrew J. Czernik，他们在 Paul Greengard 博士的实验室共同工作，Paul Greengard 博士因研究蛋白质磷酸化在信号转导中的作用而共同获得 2000 年诺贝尔医学奖在神经系统中。这种专业知识使我们主要关注神经科学领域中感兴趣的蛋白质。我们位于科罗拉多州奥罗拉的 Fitzsimons 生命科学园区，是一支敬业、友好、勤奋的科学家团队，致力于为您提供最优质的抗体和业内客户支持。