Rabbitpolyclonalantibody

Size:

100µl

Formulation:

AffinityPurifiedfromPooledSerum

Specificity:

Rat,Mouse,Human,Xenopus,Bovine,Chicken,Non-humanprimate,Zebrafish,Sheep,Canine

Applications:

WB1:1,000

Species:

Rabbit

MolecularReference:

~71kDa

CiteThisAntibody:

PhosphoSolutionsCat#p1125-499,RRID:AB_2492094

Storage

100µlin10mMHEPES(pH7.5),150mMNaCl,100µgpermlBSAand50%glycerol.Adequateamountofmaterialtoconduct10-miniWesternBlots.

Forlongtermstorage–20°Cisrecommended.Stableat–20°Cforatleast1year.

ProductSpecificReferences

Bartley,C.M.,O’Keefe,R.A.,Blice-Baum,A.,Mihailescu,M.R.,Gong,X.,Miyares,L.,Karaca,E.andBordey,A.,2016.MammalianFMRPS499isphosphorylatedbyCK2andpromotessecondaryphosphorylationofFMRP.eneuro,pp.ENEURO-0092. PMID: 27957526 

Guimarães-Souza,E.M.,Perche,O.,Morgans,C.W.,Duvoisin,R.M.,&Calaza,K.C.(2016).FragileXMentalRetardationProteinexpressionintheretinaisregulatedbylight.ExperimentalEyeResearch,146,72-82.PMID:26719241

Reynolds,C.D.,Smith,G.D.,Jefferson,T.S.,&Lugo,J.N.(2014).ComparisonofEquivalencebetweenTwoCommerciallyAvailableS499-PhosphorylatedFMRPAntibodiesinMice.PloSone,10(11),e0143134-e0143134.PMID:26580204

BartleyCM,O’KeefeRA,BordeyA(2014)FMRPS499isphosphorylatedindependentofmTORC1-S6K1activity.PLoSOne.9(5):e96956.PMID:24806451

BernardPB,CastanoAM,O’LearyH,SimpsonK,BrowningMD,BenkeTA.(2013)PhosphorylationofFMRPandalterationsofFMRPcomplexunderlieenhancedmLTDinadultratstriggeredbyearlylifeseizures.NeurobiolDis.Nov;59:1-17.PMID:23831253

PhosphoSolutions 由 Drs 于 2001 年创立。Michael D. Browning、John W. Haycock 和 Andrew J. Czernik，他们在 Paul Greengard 博士的实验室共同工作，Paul Greengard 博士因研究蛋白质磷酸化在信号转导中的作用而共同获得 2000 年诺贝尔医学奖在神经系统中。这种专业知识使我们主要关注神经科学领域中感兴趣的蛋白质。我们位于科罗拉多州奥罗拉的 Fitzsimons 生命科学园区，是一支敬业、友好、勤奋的科学家团队，致力于为您提供最优质的抗体和业内客户支持。