Rabbit polyclonalantibody

Size:

100µl

Formulation:

AffinityPurifiedfromPooledSerum

Specificity:

Rat,Mouse,Bovine,Canine

Applications:

WB1:1000

Species:

Rabbit

GeneName:

AQP2

MolecularReference:

~29kDa

CiteThisAntibody:

PhosphoSolutionsCat#p112-269,RRID:AB_2492043

Storage

100µlin10mMHEPES(pH7.5),150mMNaCl,100µgpermlBSAand50%glycerol.Adequateamountofmaterialtoconduct10-miniWesternBlots.

Forlongtermstorage–20°Cisrecommended.Stableat–20°Cforatleast1year.

ProductSpecificReferences

Lei,L.,Huang,M.,Su,L.,Xie,D.,Mamuya,F.A.,Ham,O.,Tsuji,K.,Păunescu,T.G.,Yang,B.andLu,H.A.J.,2017.ManganesepromotesintracellularaccumulationofAQP2viamodulatingF-actinpolymerizationandreducesurinaryconcentrationinmice.AmericanJournalofPhysiology-RenalPhysiology,Oct18:ajprenal-00391.PMID:29046300

Yui,N.,Ando,F.,Sasaki,S.andUchida,S.,2017.Ser-261phospho-regulationisinvolvedinpS256andpS269-mediatedaquaporin-2apicaltranslocation.BiochemicalandBiophysicalResearchCommunications.2017Jun28. PMID:28668390

Yui,N.,Sasaki,S.andUchida,S.,2016.Aquaporin-2Ser-261phosphorylationisregulatedincombinationwithSer-256andSer-269phosphorylation.BiochemicalandBiophysicalResearchCommunications. 2017Jan22;482(4):524-529.PMID: 27889609

Gao,Y.,Stuart,D.,Pollock,J.S.,Takahashi,T.andKohan,D.E.,2016.Collectingduct-specificknockoutofnitricoxidesynthase3impairswaterexcretioninasex-dependentmanner.AmericanJournalofPhysiology-RenalPhysiology,pp.ajprenal-00494.PMID:27707708

Speed,J.S.,&Hyndman,K.A.(2016).Invivoorganspecificdrugdeliverywithimplantableperistalticpumps.Scientificreports,6.PMID:27185292

Choi,H.J.,Jung,H.J.,&Kwon,T.H.(2015).ExtracellularpHaffectsphosphorylationandintracellulartraffickingofAQP2ininnermedullarycollectingductcells.AmericanJournalofPhysiology-RenalPhysiology,308(7),F737-F748.PMID:25651562

MamenkoM,DhandeI,TomilinV,ZaikaO,BoukelmouneN,ZhuY,Gonzales-GarayML,PochynyukO,&Doris,P.(2015)DefectiveStore-OperatedCalciumEntryCausesPartialNephrogenicDiabetesInsipidus.J.Am.Soc.Nephrol.Nov16.PMID:26574044

Rice,W.L.,Li,W.,Mamuya,F.,McKee,M.,Păunescu,T.G.,&Lu,H.A.J.(2015).PolarizedTraffickingofAQP2RevealedinThreeDimensionalEpithelialCulture.PloSone,10(7),e0131719.PMID:26147297

Hoffert,J.D.,Pisitkun,T.,Saeed,F.,Wilson,J.L.,&Knepper,M.A.(2014).GlobalanalysisoftheeffectsoftheV2receptorantagoNISTsatavaptanonproteinphosphorylationincollectingduct.AmericanJournalofPhysiology-RenalPhysiology,306(4),410-421.PMID:24259510

Bogum,J.,Faust,D.,Zühlke,K.,Eichhorst,J.,Moutty,M.C.,Furkert,J.,EldahshanA,NeuenschwanderM,vonKriesJP,WiesnerB,&Trimpert,C.(2013).Small-moleculescreeningidentifiesmodulatorsofaquaporin-2trafficking.JournaloftheAmericanSocietyofNephrology,24(5),744-758.PMID: 23559583

HoffertJD,FentonRA,MoellerHB,SimonsB,TchapyjnikovD,McDillBW,YuMJ,PisitkunT,ChenF,KnepperMA.(2008)Vasopressin-stimulatedincreaseinphosphorylationatserine269potentiatesplasmamembraneretentionofaquaporin2.JBiolChem.2008Sep5;283(36):24617-27.PMID:18606813

PhosphoSolutions 由 Drs 于 2001 年创立。Michael D. Browning、John W. Haycock 和 Andrew J. Czernik，他们在 Paul Greengard 博士的实验室共同工作，Paul Greengard 博士因研究蛋白质磷酸化在信号转导中的作用而共同获得 2000 年诺贝尔医学奖在神经系统中。这种专业知识使我们主要关注神经科学领域中感兴趣的蛋白质。我们位于科罗拉多州奥罗拉的 Fitzsimons 生命科学园区，是一支敬业、友好、勤奋的科学家团队，致力于为您提供最优质的抗体和业内客户支持。