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主营:神经科学领域的蛋白及抗体
℡ 4000-520-616
℡ 4000-520-616
PhosphoSolutions/RBPMS Antibody, Guinea Pig/1832-RBPMS/100 µl
产品编号:1832-RBPMS
市  场 价:¥4574.70
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$345.00
品      牌: PhosphoSolutions
公      司:PhosphoSolutions
公司分类:
PhosphoSolutions/RBPMS Antibody, Guinea Pig/1832-RBPMS/100 µl
商品介绍

Guineapigpolyclonalantibody

Size:
100µl
Formulation:
Affinitypurified
Specificity:
Rat,Mouse,Human,Non-humanprimate,Rabbit,GuineaPig
Applications:
WB1:1,000IHC1:500
Species:
GuineaPig
GeneName:
RBPMS
MolecularReference:
~24kDa
CiteThisAntibody:
PhosphoSolutionsCat#1832-RBPMS,RRID:AB_2492226
Antigen/Purification:ExpandCollapse

TheantigenisasyntheticpeptidecorrespondingtoaminoacidresiduesfromtheN-terminalregionoftheratRBPMSsequenceconjugatedtoKLH.

TheantibodyispreparedfromguineapigserumbyaffinitypurificationviachromatographyonanaffinitycolumnpreparedwiththeN-terminalpeptideusedasantigen.

BIOLOGicalSignificance:ExpandCollapse

RBPMS(RNAbindingproteinwithmultiplesplicing),alsoknownasHERMES,containsoneRRM(RNArecognitionmotif)domainandbelongstotheRRMfamilyofRNA-bindingproteins.RBPMSexistsasmultiplealternativelysplicedisoformsandisthoughttobindRNA,possIBLyplayingaroleinRNA-relatedevents,suchastranscriptionandtranslation.RNA-bindingproteinsthatarespecifictoretinalganglioncells(RGCs)havebeenpreviouslyidentifiedasexcellentMarkersforRGCs(Kwongetal.,2010).RecentfindingsshowthatantibodiesagainstRBPMSarerobustreagentsthatexclusivelyidentifyRGCsinmultiplemammalianspecies(Rodriguezetal.2014).

Storage

100µlinPBS+0.03%sodiumazide.

Forlongtermstorage–20°Cisrecommendedinundilutedaliquots.Stableat–20°Cforatleast1year.Avoidfreeze/thawcycles.

ProductSpecificReferences

Livne-Bar,I.,Wei,J.,Liu,H.H.,Alqawlaq,S.,Won,G.J.,Tuccitto,A.,Gronert,K.,Flanagan,J.G.andSivak,J.M.,2017.Astrocyte-derivedlipoxinsA4andB4promoteneuroprotectionfromacuteandchronicinjury.TheJournalofClinicalInvestigation,127(12).PMID:29106385

Ruzafa,N.,Pereiro,X.,Aspichueta,P.,Araiz,J.andVecino,E.,2017.TheRetinaofOsteopontindeficientMiceinAging.MolecularNeurobiology,pp.1-9.PMID:28866734

Peng,Y.R.,Tran,N.M.,Krishnaswamy,A.,KostADInov,D.,Martersteck,E.M.andSanes,J.R.,2017.Satb1RegulatesContactin5toPatternDendritesofaMammalianRetinalGanglionCell.Neuron.PMID:28781169

Sabbah,S.,Gemmer,J.A.,Bhatia-Lin,A.,Manoff,G.,Castro,G.,Siegel,J.K.,Jeffery,N.andBerson,D.M.,2017.Aretinalcodeformotionalongthegravitationalandbodyaxes.Nature,546(7659),pp.492-497.PMID:28607486

PérezdeSevillaMüller,L.,Solomon,A.,Sheets,K.,Hapukino,H.,Rodriguez,A.andBrecha,N.C.,2017.MultiplecelltypesformtheVIPamacrinecellpopulation.JournalofComparativeNeurology. PMID:28472856

Obara,E.A.,Hannibal,J.,Heegaard,S.andFahrenkrug,J.,2017.LossofMelanopsin-ExpressingRetinalGanglionCellsinPatientsWithDiabeticRetinopathy.InvestigativeOphthalmology&VisualScience,58(4),pp.2187-2192.PMID:28399269

Ueki,Y.,Ramirez,G.,Salcedo,E.,StABIo,M.E.andLefcort,F.,2016.LossofIkbkapcausesslow,progressiveretinaldegenerationinamousemodelofFamilialDysautonomia.eneuro,3(5),pp.ENEURO-0143.PMID:27699209

Obara,E.A.,Hannibal,J.,Heegaard,S.,&Fahrenkrug,J.(2016).LossofMelanopsin-ExpressingRetinalGanglionCellsinSeverelyStagedGlaucomaPatients.InvestigativeOphthalmology&VisualScience,57(11),4661-4667. PMID:27583827

Long,Y.,Bordt,A.S.,Liu,W.S.,Davis,E.P.,Lee,S.J.,Tseng,L.,Chuang,A.Z.,Whitaker,C.M.,Massey,S.C.,Sherman,M.B.,&Marshak,D.W.(2016).Wide-fielddiffuseamacrinecellsinthemonkeyretinacontainimmunoreactiveCocaine-andAmphetamine-RegulatedTranscript(CART).Peptides,84,22-35.PMID:27568514

Boggio,E.M.,Pancrazi,L.,Gennaro,M.,Rizzo,C.L.,Mari,F.,Meloni,I.,Ariani,F.,Panighini,A.,Novelli,E.,Biagioni,M.,Strettoi,E.,Hayek,J.,Rufa,A.,Pizzorusso,T.,Renieri,A.,&Strettoi,E.(2016).VisualimpairmentinFOXG1-mutatedindividualsandmice.Neuroscience,324,496-508. PMID:27001178

PérezdeSevillaMüller,L.,Sargoy,A.,Fernández‐Sánchez,L.,Rodriguez,A.,Liu,J.,Cuenca,N.,&Brecha,N.(2015).Expressionandcellularlocalizationofthevoltage‐gatedcalciumchannelα2δ3intherodentretina.JournalofComparativeNeurology,523(10),1443-1460.PMID:25631988

品牌介绍

PhosphoSolutions 由 Drs 于 2001 年创立。Michael D. Browning、John W. Haycock 和 Andrew J. Czernik,他们在 Paul Greengard 博士的实验室共同工作,Paul Greengard 博士因研究蛋白质磷酸化在信号转导中的作用而共同获得 2000 年诺贝尔医学奖在神经系统中。这种专业知识使我们主要关注神经科学领域中感兴趣的蛋白质。我们位于科罗拉多州奥罗拉的 Fitzsimons 生命科学园区,是一支敬业、友好、勤奋的科学家团队,致力于为您提供最优质的抗体和业内客户支持。

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