Rabbitpolyclonalantibody
Theantigenisan endogenousrabbit2,3-cyclicnucleotide-3-phospho-diesterase.
Theantibodyisneatserum.
2,3-cyclicnucleotide-3-phosphodiesterase(CNP)isamembranebound,microtubuleassociatedproteinthatisamongthemostabundantmyelinproteinsoftheCNS.ItisthoughtthatCNPmayserveasaregulatoroftubulinpolymerizationandofmicrotubuledistribution(Bifulcoetal.,2002).ItwasrecentlyfoundthatCNPmayalsofunctionasapossIBLelinkerproteinanchoringmicrotubulestotheplasmamembraneviaa13residueC-terminalCNPfragment(Bifulcoetal.,2002,Espositoetal.,2008).
50ulneatserum.
Forlongtermstorage–20°Cisrecommended.Stableat–20°Cforatleast1year.
Bifulcoetal.2,3-Cyclicnucleotide3-phosphodiesterase:amembranebound,microtubuleassociatedproteinandmembraneanchortubulin.PNAS99:1807-12,2002.
EspositoC,ScrimaM,CarotenutoA,TedeschiA,RoveroP,D’EbifulcoM,D’ErricoG,MalfitanoAM,D’UrsiAM(2008)StructuresandmicellelocationsofthenonlipidatedandlipidatedC-terminalanchorof2,3-Cyclicnucleotide3-phosphodiesterase.Biochemistry47(1):308-319.
PhosphoSolutions 由 Drs 于 2001 年创立。Michael D. Browning、John W. Haycock 和 Andrew J. Czernik,他们在 Paul Greengard 博士的实验室共同工作,Paul Greengard 博士因研究蛋白质磷酸化在信号转导中的作用而共同获得 2000 年诺贝尔医学奖在神经系统中。这种专业知识使我们主要关注神经科学领域中感兴趣的蛋白质。我们位于科罗拉多州奥罗拉的 Fitzsimons 生命科学园区,是一支敬业、友好、勤奋的科学家团队,致力于为您提供最优质的抗体和业内客户支持。