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主营:神经科学领域的蛋白及抗体
℡ 4000-520-616
℡ 4000-520-616
PhosphoSolutions/Nestin Antibody/1435-NES/100 µl
产品编号:1435-NES
市  场 价:¥4574.70
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$345.00
品      牌: PhosphoSolutions
公      司:PhosphoSolutions
公司分类:
PhosphoSolutions/Nestin Antibody/1435-NES/100 µl
商品介绍

Mousemonoclonalantibody

Size:
100µl
Formulation:
ProteinGPurified
Specificity:
Rat,Mouse,Human
Applications:
WB1:2,000IF1:500
Species:
Mouse
MolecularReference:
~220-240kDa
CiteThisAntibody:
PhosphoSolutionsCat#1435-NES,RRID:AB_2492158
Antigen/Purification:ExpandCollapse

TheantigenisarecombinantpartialsegmentofhumannestinexpressedinandpurifiedfromE.coli.

TheantibodyisProteinGpurified.

BIOLOGicalSignificance:ExpandCollapse

NestinisamemberoftheclassIVintermediatefilamentproteinfamilywhichisexpressedinneuronalstemcells(Lendahletal.,1990).Nestinwasoriginallyidentifiedasaresultoftheproductionofaseriesofmonoclonalantibodiesdirectedagainstepitopesexpressedonformalinfixedembryoday15ratspinalcord(Hockfieldetal.,1985)).Oneoftheseantibodies,calledRat401,stainedfibrousprofilesinthedevelopingnervoussystem,butnotinthematurenervoussystem.ByscreeningbacteriophageexpressionlibrarieswithRat401,Lendahletal.wereabletoisolateaCDNAencodingtheproteintowhichRat401antibodybound.Theproteinprovedtobeanunusualmemberoftheintermediatefilamentfamily,containinganalpha-helicalregionhomologoustothatfoundinkeratinandneurofilamentsubunits.

Storage

Ascitesfluid+0.01%NaN3.

Forlongtermstorage–20°Cisrecommendedinundilutedaliquots.Stableat–20°Cforuptooneyearafterdateofreceipt.Avoidfreeze/thawcycles.

ProductSpecificReference

Thakur,V.,Nargis,S.,Gonzalez,M.,Pradhan,S.,Terreros,D.andChattopadhyay,M.,2017.RoleofGlycyrrhizinintheReductionofInflammationinDiabeticKidneyDisease.Nephron.PMID:28641285

品牌介绍

PhosphoSolutions 由 Drs 于 2001 年创立。Michael D. Browning、John W. Haycock 和 Andrew J. Czernik,他们在 Paul Greengard 博士的实验室共同工作,Paul Greengard 博士因研究蛋白质磷酸化在信号转导中的作用而共同获得 2000 年诺贝尔医学奖在神经系统中。这种专业知识使我们主要关注神经科学领域中感兴趣的蛋白质。我们位于科罗拉多州奥罗拉的 Fitzsimons 生命科学园区,是一支敬业、友好、勤奋的科学家团队,致力于为您提供最优质的抗体和业内客户支持。

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