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主营:神经科学领域的蛋白及抗体
℡ 4000-520-616
℡ 4000-520-616
PhosphoSolutions/Vesicular GABA Amino Acid Transporter (VGAT) Antibody/2100-VGAT/100 µl
产品编号:2100-VGAT
市  场 价:¥4574.70
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$345.00
品      牌: PhosphoSolutions
公      司:PhosphoSolutions
公司分类:
PhosphoSolutions/Vesicular GABA Amino Acid Transporter (VGAT) Antibody/2100-VGAT/100 µl
商品介绍

Rabbitpolyclonalantibody

PooledSerum
Size:
100µl
Formulation:
AffinityPurifiedfromPooledSerum
Specificity:
Bovine,Canine,Chicken,Mouse,Non-humanprimate,Rat
Applications:
WB1:1,000
Species:
Rabbit
GeneName:
SLC32A1
MolecularReference:
~53kDa
CiteThisAntibody:
PhosphoSolutionsCat#2100-VGAT,RRID:AB_2492282
Antigen/Purification:ExpandCollapse

TheantigenisapeptidecorrespondingtoaminoacidresiduesfromtheN-terminalregionofratVesicularGABAAminoAcidTransporter(VGAT).

Theantibodyispreparedfromrabbitserumbyaffinitypurificationonacolumnmadewiththepeptideusedasantigen.

BIOLOGicalSignificance:ExpandCollapse

TheVesicularGABAAminoAcidTransporter(VGAT)isresponsIBLefortransportoftheinhibitoryneurotransmitterintosynapticvesicles(McIntireetal.,1997).TheVGATprotein(alsoknownastheVesicularInhibitoryAminoAidTransporterorVIAAT)isexpressedinsynapticvesiclesofbothglycineandGABAergicsynapsesthroughouttheCNS(Chaudhryetal.,1998).ExpressionoftheVGATproteinchangesduringdevelopmentandalsoinresponsetopatternsofneuronalactivity(Deetal.,2005).

Storage

Liquid.Contains10mMsodiumazide.

Forlongtermstorage–20°Cisrecommendedinundilutedaliquots.Stableat–20°Cforatleast1year.Avoidfreeze/thawcycles.

ProductSpecificReferences

Ka,M.,Kook,Y.H.,Liao,K.,Buch,S.andKim,W.Y.,2016.TransactivationofTrkBbySigma-1receptormediatescocaine-inducedchangesindendriticspinedensityandmorphologyinhippocampalandcorticalneurons.CellDeath&Disease,7(10),p.e2414.PMID:27735948

Ka,M.,Chopra,D.A.,Dravid,S.M.,&Kim,W.Y.(2016).EssentialRolesforARID1BinDendriticArborizationandSpineMorphologyofDevelopingPyramidalNeurons.TheJournalofNeuroscience,36(9),2723-2742.PMID:26937011

Rotschafer,S.E.,Marshak,S.,&Cramer,K.S.(2015).DeletionofFmr1AltersFunctionandSynapticInputsintheAuditoryBrainstem.PloSone,Feb13;10(2):e0117266.PMID:25679778

Noseda,R.,Kainz,V.,Borsook,D.,&Burstein,R.(2014).NeuRochemicalpathwaysthatconvergeonthalamictrigeminovascularneurons:potentialsubstrateformodulationofmigrainebysleep,foodintake,stressandanxiety.PLoSOne.Aug4;9(8):e103929.PMID:25090640

品牌介绍

PhosphoSolutions 由 Drs 于 2001 年创立。Michael D. Browning、John W. Haycock 和 Andrew J. Czernik,他们在 Paul Greengard 博士的实验室共同工作,Paul Greengard 博士因研究蛋白质磷酸化在信号转导中的作用而共同获得 2000 年诺贝尔医学奖在神经系统中。这种专业知识使我们主要关注神经科学领域中感兴趣的蛋白质。我们位于科罗拉多州奥罗拉的 Fitzsimons 生命科学园区,是一支敬业、友好、勤奋的科学家团队,致力于为您提供最优质的抗体和业内客户支持。

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