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主营:神经科学领域的蛋白及抗体
℡ 4000-520-616
℡ 4000-520-616
PhosphoSolutions/Olig2 Antibody/1538-Olig2/100 µl
产品编号:1538-Olig2
市  场 价:¥4574.70
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$345.00
品      牌: PhosphoSolutions
公      司:PhosphoSolutions
公司分类:
PhosphoSolutions/Olig2 Antibody/1538-Olig2/100 µl
商品介绍

Rabbitpolyclonalantibody

Size:
100µl
Formulation:
ProteinAPurified
Specificity:
Rat,Mouse,Human
Applications:
WB1:3,000IHC1:1,000IP1:500-1:1,000
Species:
Rabbit
MolecularReference:
~32kDa
CiteThisAntibody:
PhosphoSolutionsCat#1538-Olig2,RRID:AB_2492193
Antigen/Purification:ExpandCollapse

TheantigenisarecombinantmouseOlig2.

TheantibodyisProteinApurifiedrabbitserum.

BIOLOGicalSignificance:ExpandCollapse

Olig2isatranscriptionfactorwhichisrequiredforoligodendrocyteandmotorneuronspecificationinthespinalcord,aswellasforthedevelopmentofsomaticmotorneuronsinthehindbrain.Expressedintheventralspinalcordasearlyas9.5dpcandscatteredinthemantlezone,likelycorrespondingtooligodendrocyteProgenitorsmigratingoutfromtheirsiteoforigin.From10.5through14.5dpc,Olig2isexpressedinnumerouscellsintheventricularandsubventricularzonesofthelateralandmedialganglioniceminences,suggestingthatexpressionmightnotbelimitedtotheoligodendrocyticlineage.Olig2hasfurtherbeenshowntobecriticalintheproliferationofmalignantgliomainbraintumors(Ligonetal.,2007)

Storage

Liquidin100mMGlycine,200mMTris,pH8.0.Containsnopreservative.

Forlongtermstorage–20°Cisrecommendedinundilutedaliquots.Stableat–20°Cforforuptooneyearafterdateofreceipt.Avoidfreeze/thawcycles.

ProductSpecificReferences

Kucharova,K.,&Stallcup,W.B.(2015).NG2-proteoglycan-dependentcontributionsofoligodendrocyteprogenitorsandmyeloidcellstomyelindamageandrepair.Journalofneuroinflammation,12(1),161.PMID:26338007

Mauney,S.A.,Pietersen,C.Y.,Sonntag,K.C.,&Woo,T.U.W.(2015).Differentiationofoligodendrocyteprecursorsisimpairedintheprefrontalcortexinschizophrenia.SchizophreniaResearch,169(1),374-380.PMID:26585218

NorwoodJ,FranklinJM,SharmaD,D’MelloSR(2014)Histonedeacetylase3isnecessaryforproperbraindevelopment.JBiolChem.2014Dec12;289(50):34569-34582.PMID:25339172

品牌介绍

PhosphoSolutions 由 Drs 于 2001 年创立。Michael D. Browning、John W. Haycock 和 Andrew J. Czernik,他们在 Paul Greengard 博士的实验室共同工作,Paul Greengard 博士因研究蛋白质磷酸化在信号转导中的作用而共同获得 2000 年诺贝尔医学奖在神经系统中。这种专业知识使我们主要关注神经科学领域中感兴趣的蛋白质。我们位于科罗拉多州奥罗拉的 Fitzsimons 生命科学园区,是一支敬业、友好、勤奋的科学家团队,致力于为您提供最优质的抗体和业内客户支持。

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