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主营:神经科学领域的蛋白及抗体
℡ 4000-520-616
℡ 4000-520-616
PhosphoSolutions/Calretinin Antibody/303-CAL/100 µl
产品编号:303-CAL
市  场 价:¥4574.70
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$345.00
品      牌: PhosphoSolutions
公      司:PhosphoSolutions
公司分类:
PhosphoSolutions/Calretinin Antibody/303-CAL/100 µl
商品介绍

Sheeppolyclonalantibody

Size:
100µl
Formulation:
ProteinGpurified
Specificity:
Rat,Mouse,Human,Non-humanprimate
Applications:
WB1:1,000IF1:500IHC1:500
Species:
Sheep
MolecularReference:
~29kDa
CiteThisAntibody:
PhosphoSolutionsCat#303-CAL,RRID:AB_2492050
Antigen/Purification:ExpandCollapse

Theantigenisa  purifiedguineapigcalretinin.

TheantibodyisproteinApurifiedsheepserum.

BIOLOGicalSignificance:ExpandCollapse

Calretininisacalcium-bindingproteininvolvedincalciumsignaling.Itisabundantlyexpressedthroughoutthecentralnervoussystem,retinaandmanyothertissues.Studieshaveshownthatcalretininmayplayaroleinneuroprotectionbybufferingintracellularcalcium(LukasandJones1994,Weisenhornetal.,1996).Additionally,calretininselectivelystainsmesothelialcellsthusmakingitanimportantMarkerfordifferentiatingmalignantmesotheliomafromcarcinomas(Attanoosetal.,2000).

Storage

100µlin10mMTris,100mMNaCl.

Forlongtermstorage–20°Cisrecommendedinundilutedaliquots.Stableat–20°Cforatleast1year.Avoidfreeze/thawcycles.

GeneralReferences

AttanoosRL,DojcinovSD,WebbR,GibbsAR.(2000)Anti-mesothelialmarkersinsarcomatoidmesotheliomaandotherspindlecellneoplasms.Histopathology.37(3):224-31.

IsaacsKR,WinskyL,StraussKI,JacobowitzDM.(1995)Quadruplecolocalizationofcalretinin,calcitoningene-relatedpeptide,vasoactiveintestinalpeptide,andsubstancePinfiberswithinthevillioftheratintestine.CellTissueRes.,280(3):639-51.

LukasW,JonesKA(1994)Corticalneuronscontainingcalretininareselectivelyresistanttocalciumoverloadandexcitotoxicityinvitro.Neurosci.61(2):307-16.

WeisenhornDMV,Weruaga-PrietoE,CelioMR(1996)Calretininimmunoreactivityinorganotypicculturesoftheratcerebralcortex:effectsofserumdeprivation.Exp.BrainRes.108(1):101-112.

品牌介绍

PhosphoSolutions 由 Drs 于 2001 年创立。Michael D. Browning、John W. Haycock 和 Andrew J. Czernik,他们在 Paul Greengard 博士的实验室共同工作,Paul Greengard 博士因研究蛋白质磷酸化在信号转导中的作用而共同获得 2000 年诺贝尔医学奖在神经系统中。这种专业知识使我们主要关注神经科学领域中感兴趣的蛋白质。我们位于科罗拉多州奥罗拉的 Fitzsimons 生命科学园区,是一支敬业、友好、勤奋的科学家团队,致力于为您提供最优质的抗体和业内客户支持。

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