Rabbitpolyclonalantibody

Size:

100µl

Formulation:

AffinityPurifiedfromPooledSerum

Specificity:

Rat,Mouse,Human,Non-humanprimate,Zebrafish,GuineaPig

Applications:

WB1:1000

Species:

Rabbit

MolecularReference:

~25kDa

CiteThisAntibody:

PhosphoSolutionsCat#p1558-187,RRID:AB_2492239

Storage

100µlin10mMHEPES(pH7.5),150mMNaCl,100µgBSApermland50%glycerol.Adequateamountofmaterialtoconduct10-miniWesternBlots.

Forlongtermstorage–20°Cisrecommended.Stableat–20°Cforatleast1year.

GeneralReferences

AndoK,KudoY,TakahashiM(2005)Negativeregulationofneurotransmitterreleasebycalpain:apossIBLespecificinvolvementofSnap25cleavage.JNeuRochem94(3):651-8.

FatemiSH,EarleJA,StaryJM,LeeS,SedgwickJ(2001)AlteredlevelsofthesynaptosomalassociatedproteinSnap25inhippocampusofpatientswithmooddisordersandSchizophrenia.Neuroreport.12(15):3257-62.

FatemiSH,SidwellR,KistD,AkhterP,MeltzerHY,BaileyK,ThurasP,SedgwickJ(1998)Differentialexpressionofsynaptosome-associatedprotein25kDa(Snap25)inhippocampiofneonatalmicefollowingexposuretohumaninfluenzavirusinutero.BrainRes800(1):1-9.

GreberS,CairnsN,LubecG,FountoulakisM(1999)Decreasedlevelsofthesynaptosomalassociatedprotein25inthebrainsofpatientswithDownSyndromeandAlzheimer’sDisease.Electrophoresis20(4-5):928-34.

PozziD,CondliffeS,BozziY,ChikhladzeM,GrumelliC,Proux-GillardeauxV,TakahashiM,FranceschettiS,VerderioC,MatteoliM(2008)Activity-dependentphosphorylationofSer187isrequiredforSNAP-25-negativemodulationofneuronalvoltage-gatedcalciumchannels.PNAS105:323-328.

ShuY,LiuX,YangY,TakahashiM,GillisKD(2008)PhosphorylationofSNAP-25atSer187MediatesEnhancementofExocytosisbyaPhorbolEsterinINS-1Cells.JofNeurosci28:21-30.

PhosphoSolutions 由 Drs 于 2001 年创立。Michael D. Browning、John W. Haycock 和 Andrew J. Czernik，他们在 Paul Greengard 博士的实验室共同工作，Paul Greengard 博士因研究蛋白质磷酸化在信号转导中的作用而共同获得 2000 年诺贝尔医学奖在神经系统中。这种专业知识使我们主要关注神经科学领域中感兴趣的蛋白质。我们位于科罗拉多州奥罗拉的 Fitzsimons 生命科学园区，是一支敬业、友好、勤奋的科学家团队，致力于为您提供最优质的抗体和业内客户支持。